Healthy Skepticism Library item: 8400

Warning: This library includes all items relevant to health product marketing that we are aware of regardless of quality. Often we do not agree with all or part of the contents.

Publication type: Journal Article

Jenne JW.
Unintentional overdose of theophylline: challenge to the pharmaceutical industry.
Clin Pharm 1984 Sep-Oct; 3:(5):523-4

Abstract:

The toxicities associated with unintentional overdose of theophylline (I), due to patient errors and overprescribing by physicians, unrecognized drug interactions and cumulative effects of sustained-action I preparations, are discussed. It was suggested that, due to the low therapeutic index of I, the pharmaceutical industry, health practitioners and FDA should devise dispensing techniques and precautionary measures that will eliminate unintentional overdose.

Keywords:
Dosage Forms Drug Industry Humans Theophylline/poisoning*