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Healthy Skepticism Library

Items published in 2011

There are 502 items in the Healthy Skepticism Library that were published in 2011.

Page 3 of 6 pages  < 1 2 3 4 5 >  Last ›

HSL19450
Kirchgaessner S
Big Pharma faces challenge on drug prices
The Finanical Times 2011 Mar 29
http://www.ft.com/cms/s/0/aadf4ef4-5a2d-11e0-86d3-00144feab49a.html

HSL19434
Arnold M
Docs value details, says PhRMA survey
Medical Marketing & Media 2011 Mar 29
http://www.mmm-online.com/docs-value-details-says-phrma-survey/article/199481/

HSL19435
Silverman E
Drugmakers Cannot Be Sued For Overcharging
Pharmalot 2011 Mar 29
http://www.pharmalot.com/2011/03/drugmakers-cannot-be-sued-for-overcharging/

HSL19454
Nissen SE
Can We Trust Cardiovascular Practice Guidelines?
Arch Intern Med 2011 Mar 28; 171:(6):584
http://archinte.ama-assn.org/cgi/content/extract/171/6/584

HSL19448
Saunders C
More proof vitamin pills do little
MJA InSight 2011 Mar 28;
http://www.mjainsight.com.au/

HSL19438
Mendelson TB, Meltzer M, Campbell EG, Caplan AL, Kirkpatrick JN
Conflicts of Interest in Cardiovascular Clinical Practice Guidelines
Arch Intern Med 2011 Mar 28; 171:(6):577-584
http://archinte.ama-assn.org/cgi/content/abstract/171/6/577

HSL19429
Beasley D
Branded Drug Prices Soar as Generic Pressure Rises
Reuters 2011 Mar 28
http://www.foxbusiness.com/personal-finance/2011/03/28/branded-drug-prices-soar-generic-pressure-rises/#ixzz1Hxrd12Ie

HSL19423
Kang Lim B
China cuts maximum retail price of drugs to help tame inflation
Reuters 2011 Mar 28
http://www.reuters.com/article/2011/03/28/china-pharmaceutical-idUSL3E7ES0K920110328

HSL19422
Silverman E
The Supreme Court, Generic Labels & Preemption
Pharmalot 2011 Mar 28
http://www.pharmalot.com/2011/03/the-supreme-court-generic-labels-preemption/

HSL19421
Silverman E
Novartis, The iPad & 35,000 More Visits To Docs
Pharmalot 2011 Mar 28
http://www.pharmalot.com/2011/03/novartis-the-ipad-35000-more-visits-to-docs/

HSL19449
Kumar S, Nash DB
Health Care Myth Busters: Is There a High Degree of Scientific Certainty in Modern Medicine?
Scientific American 2011 Mar 25
http://www.scientificamerican.com/article.cfm?id=demand-better-health-care-book

HSL19464
Edwards J
Internal J&J Emails Detail 'Ugly' Chapter in Mismarketing of Antipsychotics
BNet 2011 Mar 25
http://www.bnet.com/blog/drug-business/internal-j-j-emails-detail-8220ugly-8221-chapter-in-mismarketing-of-antipsychotics/7743

HSL19424
Arnold M
One fourth of family medicine residencies pharma free says survey
Medical Marketing & Media 2011 Mar 25
http://www.mmm-online.com/one-fourth-of-family-medicine-residencies-pharma-free-says-survey/article/199268/

HSL19418
Lexchin J
Canada's Patented Medicine Notice of Compliance Regulations: Balancing the Scales or Tipping Them?
BMC Health Services Research 2011 2011 Mar 24; 11:(64):
http://www.biomedcentral.com/1472-6963/11/64/abstract

HSL19411
Silverman E
Hide Side Effect Reports And Investors Can Sue
Pharmalot 2011 Mar 23
http://www.pharmalot.com/2011/03/hide-side-effect-reports-and-investors-can-sue/

HSL19459
IMS Health Launches Institute for Healthcare Informatics
IMS Health 2011 Mar 23
http://www.imshealth.com/portal/site/imshealth/menuitem.a46c6d4df3db4b3d88f611019418c22a/?vgnextoid=a1e57460380ee210VgnVCM100000ed152ca2RCRD&vgnextchannel=41a67900b55a5110VgnVCM10000071812ca2RCRD&vgnextfmt=default

HSL19426
Fugh-Berman A, Brown SR, Trippett R, Bell AM, Clark P, Fleg A, Siwek J
Closing the Door on Pharma? A National Survey of Family Medicine Residencies Regarding Industry Interactions
Acad Med. 2011 Mar 23;
http://journals.lww.com/academicmedicine/Abstract/publishahead/Closing_the_Door_on_Pharma__A_National_Survey_of.99863.aspx

HSL19409
Benkimoun P
France proposes overhaul of drug regulatory system
MJA 2011 Mar 23; 342:
http://www.bmj.com/content/342/bmj.d1829.extract

HSL19410
Silverman E
J&J Faces $360M Penalty Over Risperdal Marketing
Pharmalot 2011 Mar 23
http://www.pharmalot.com/2011/03/jj-faces-360m-penalty-over-risperdal-marketing/

HSL19408
Garrison L
Is America prescribing too many drugs?
wptv 2011 Mar 22
http://www.wptv.com/dpp/news/national/is-america-prescribing-too-many-drugs%3F

HSL19499
Barnett J
How Quick Response codes can help pharma engage with patients
eyeforpharma.com 2011 Mar 22
http://social.eyeforpharma.com/story/how-quick-response-codes-can-help-pharma-engage-patients

HSL19415
Silverman E
Lilly Pulls Down Strattera Web Site In China
Pharmalot 2011 Mar 21
http://www.pharmalot.com/2011/03/lilly-pulls-down-strattera-web-site-in-china/

HSL19404
Jack A
Former pharma watchdog faces restrictions
The Finanical Times 2011 Mar 21
http://www.ft.com/cms/s/0/73c0a4aa-53ce-11e0-a01c-00144feab49a.html#axzz1Hn0XT9Aj

HSL19412
Edwards J
See No Evil: How Too-Detailed Expense Reports Allegedly Got an Amgen Sales Rep Fired
BNet 2011 Mar 21
http://www.bnet.com/blog/drug-business/see-no-evil-how-too-detailed-expense-reports-allegedly-got-an-amgen-sales-rep-fired/7671

HSL19406
Branded Pharmaceutical Websites Continue to Be Most Impactful in Driving Conversions Among Prospects and Patients
Pharma Live 2011 Mar 21
http://pharmalive.com/news/index.cfm?articleID=769109

HSL19419
Jagosh J, Pluye P, Macaulay AC, Salsberg J, Henderson J, Sirett E, Bush PL, Seller R, Wong G, Greenhalgh T, Cargo M, Herbert CP, Seifer SD, Green LW
Assessing the outcomes of participatory research: protocol for identifying, selecting, appraising and synthesizing the literature for realist review
Implementation Science 2011 Mar 20; 6:(1):24
http://www.implementationscience.com/content/6/1/24/abstract

HSL19433
Church S, Pettersson E
Bristol-Myers Bribed Doctors in Drug Scheme, California Commissioner Says
Bloomberg News 2011 Mar 19
http://www.bloomberg.com/news/2011-03-18/bristol-myers-bribed-doctors-in-drug-scheme-california-commissioner-says.html

HSL19416
Silverman E
California Joins Whistleblower Suit Against Bristol
Pharmalot 2011 Mar 18
http://www.pharmalot.com/2011/03/california-joins-whistleblower-suit-against-bristol/

HSL19440
Gaidos M
Hunting Ghosts
Science 2011 Mar 18
http://sciencecareers.sciencemag.org/career_magazine/previous_issues/articles/2011_03_18/caredit.a1100025

HSL19439
Silverman E
‘There Is A Louse In Your House… And Your Ad’
Pharmalot 2011 Mar 18
http://www.pharmalot.com/2011/03/there-is-a-louse-in-your-house-and-your-ad/

HSL19417
Silverman E
Senators Ask FTC To Probe KV For Price Gouging
Pharmalot 2011 Mar 18
http://www.pharmalot.com/2011/03/senators-ask-ftc-to-probe-kv-for-price-gouging/

HSL19366
Mashta O
Herbal medicines will need to be registered with drug regulator to be sold in UK
BMJ 2011 Mar 17; 342:
http://www.bmj.com/content/342/bmj.d1733.extract

HSL19441
Silverman E
OxyContin, Prescribing Habits & Pharma Influence
Pharmalot 2011 Mar 17
http://www.pharmalot.com/2011/03/oxycontin-presribing-habits-pharma-influence/

HSL19413
Edwards J
How Drug Companies Look at Your Private Medical Records Any Time They Want
BNet 2011 Mar 17
http://www.bnet.com/blog/drug-business/how-drug-companies-look-at-your-private-medical-records-any-time-they-want/7653

HSL19365
Spence D
We need a Sunshine Act in the UK
BMJ 2011 Mar 16; 342:
http://www.bmj.com/content/342/bmj.d1647.extract

HSL19446
Metherell M
Berocca invigorating advertising claim 'misleading'
The Sydney Morning Herald 2011 Mar 16
http://www.smh.com.au/national/berocca-invigorating-advertising-claim-misleading-20110315-1bvv2.html

HSL19443
Julious SA, Pyke S, Hughes S,
Best practice for statisticians in industry sponsored trials
BMJ 2011 Mar 15; 342:
http://www.bmj.com/content/342/bmj.d1636.extract

HSL19414
Edwards J
10 Reasons Drug Prices Always Go Up — and What We Can Do About It
BNet 2011 Mar 15
http://www.bnet.com/blog/drug-business/10-reasons-drug-prices-always-go-up-8212-and-what-we-can-do-about-it/7621

HSL19342
McDonald AM, Treweek S, Shakur H, Free C, Knight R, Speed C, Campbell MK
Using a business model approach and marketing techniques for recruitment to clinical trials
Trials 2011 Mar 11; 12:(1):74
http://www.trialsjournal.com/content/12/1/74

HSL19307
Silverman E
Peter Rost Takes Another Whack At Pfizer
Pharmalot 2011 Mar 11
http://www.pharmalot.com/2011/03/peter-rost-takes-another-whack-at-pfizer/

HSL19343
Cronin Fisk M, Feeley J
AstraZeneca to Pay $68.5 Million to U.S. States Over Seroquel Marketing
Bloomberg News 2011 Mar 11
http://www.bloomberg.com/news/2011-03-10/astrazeneca-to-pay-68-5-million-to-states-over-seroquel-marketing-claims.html

HSL19364
Silverman E
PR Firms, Drugmakers & Medical Societies
Pharmalot 2011 Mar 11
http://www.pharmalot.com/2011/03/pr-firms-drugmakers-medical-societies/

HSL19362
Grogan K
AstraZeneca settles Seroquel multi-state marketing probe
Pharma Times 2011 Mar 11
http://www.pharmatimes.com/Article/11-03-11/AstraZeneca_settles_Seroquel_multi-state_marketing_probe.aspx

HSL19357
Silverman E
Singing The Blues: A Merck LP & An Antidepressant
Pharmalot 2011 Mar 11
http://www.pharmalot.com/2011/03/singing-the-blues-a-merck-lp-an-antidepressant/

HSL19329
Ranjan Mishra A
Compulsory licensing norms soon
LiveMint.com 2011 Mar 10
http://www.livemint.com/2011/03/10001510/Compulsory-licensing-norms-soo.html?h=B

HSL19367
Kassirer JP
Keeping big pharma in check?
BMJ 2011 Mar 10; 342:
http://www.bmj.com/content/342/bmj.d1103.extract?sid=f86e3b06-ab59-4d11-ba55-6d86ee790f12

HSL19363
Galloway G
House approves generic-drug bill meant to help poor countries
The Globe and Mail 2011 Mar 10
http://www.theglobeandmail.com/news/politics/house-approves-generic-drug-bill-meant-to-help-poor-countries/article1935976/

HSL19360
Silverman E
WHO Pandemic Moves Not Swayed By Pharma
Pharmalot 2011 Mar 10
http://www.pharmalot.com/2011/03/who-pandemic-moves-not-swayed-by-pharma/

HSL19447
Kassirer JP
Keeping big pharma in check?
BMJ 2011 Mar 10; 342:
http://www.bmj.com/content/342/bmj.d1103.extract

HSL19361
Silverman E
Insider Trading, Drug Stocks & Loose-Lipped Docs
Pharmalot 2011 Mar 9
http://www.pharmalot.com/2011/03/insider-trading-drug-stocks-loose-lipped-docs/

HSL19359
Chatterjee S
Is This the End of Big Pharma?
The Motley Fool 2011 Mar 9
http://www.fool.com/investing/general/2011/03/09/is-this-the-end-of-big-pharma.aspx

HSL19430
Preemie Birth Preventive Spikes From $10 To $1,500
npr 2011 Mar 9
http://yourlife.usatoday.com/parenting-family/pregnancy/story/2011/03/Preemie-birth-preventive-spikes-from-10-to-1500/44698212/1

HSL19345
Silverman E
Those Non-Branded DTC Ads Seem To Be Working
Pharmalot 2011 Mar 8
http://www.pharmalot.com/2011/03/those-non-branded-dtc-ads-seem-to-be-working/

HSL19349
Iafolla C
Strategy Setting: A Cautionary Tale
MediaPost Marketing: Health Blogs 2011 Mar 8
http://www.mediapost.com/publications/?fa=Articles.showArticle&art_aid=146248

HSL19350
Iskowitz M
Supremes won't revisit Bayer pay-for-delay case; FTC vows to press on
Medical Marketing & Media 2011 Mar 8
http://www.mmm-online.com/supremes-wont-revisit-bayer-pay-for-delay-case-ftc-vows-to-press-on/article/197914/

HSL19356
Feeley J, Henderson G
J&J Misled South Carolina Officials About Drug, Jury Told
Bloomberg News 2011 Mar 8
http://www.bloomberg.com/news/2011-03-08/j-j-misled-south-carolina-officials-about-risperdal-jury-told.html

HSL19355
Jack A
A sugared pill
The Finanical Times 2011 Mar 8
http://www.ft.com/cms/s/0/ae7099a0-49bc-11e0-acf0-00144feab49a.html#axzz1Gwb5fZso

HSL19348
Silverman E
Supreme Court Rejects Challenge To Pay-To-Delay
Pharmalot 2011 Mar 7
http://www.pharmalot.com/2011/03/supreme-court-rejects-challenge-to-pay-to-delay/

HSL19354
Beckford M
Quarter of doctors failed to report incompetent colleague
The Telegraph 2011 Mar 7
http://www.telegraph.co.uk/health/healthnews/8366746/Quarter-of-doctors-failed-to-report-incompetent-colleague.html

HSL19319
Harvey K
Ken Harvey: The risks from vague medicine labels
MJA InSight 2011 Mar 7;
http://www.mjainsight.com.au/view?post=Ken+Harvey%3A+The+risks+from +vague+medicine+labels&post_id=3572

HSL19317
Thomaselli R
Looking for Guidance, Pharma Left Waiting
Advertising Age 2011 Mar 7
http://adage.com/article/news/drug-makers-wait-fda-ruling-social-media-dtc-ads/149214/

HSL19323
Harris G
Talk Doesn’t Pay, So Psychiatry Turns Instead to Drug Therapy
The New York Times 2011 Mar 6
http://www.nytimes.com/2011/03/06/health/policy/06doctors.html?_r=1

HSL19315
Wilson D
Drug Firms Face Billions in Losses in ’11 as Patents End
The New York Times 2011 Mar 6
http://www.nytimes.com/2011/03/07/business/07drug.html?_r=1

HSL19320
Goldacre B
Drug trial secrecy leaves us dependent on blind faith
The Guardian 2011 Mar 5
http://www.guardian.co.uk/commentisfree/2011/mar/05/bad-science-drug-trial-secrecy

HSL19352
Experts call for clearer medicine labelling
NursingTimes.net 2011 Mar 4
http://www.nursingtimes.net/whats-new-in-nursing/news-topics/public-health/experts-call-for-clearer-medicine-labelling/5026755.article

HSL19316
Silverman E
Lawsuit Over J&J Risperdal Marketing Can Proceed
Pharmalot 2011 Mar 4
http://www.pharmalot.com/2011/03/lawsuit-over-jj-risperdal-marketing-can-proceed/

HSL19314
How Are Physicians Responding to the FDA's Bad Ad Program?
Pharma Live 2011 Mar 4
http://pharmalive.com/news/index.cfm?articleID=766168

HSL19451
Silverman E
Most Docs Are Unaware Of FDA ‘Bad Ad’ Program
Pharmalot 2011 Mar 4
http://www.pharmalot.com/2011/03/most-docs-are-unaware-of-fda-bad-ad-program/

HSL19716
Gever J
New Twist in Colloids-Crystalloids Tussle
MedPage Today 2011 Mar 4
http://www.medpagetoday.com/Anesthesiology/Anesthesiology/25198

HSL19301
Zarin DA, Tse T, Williams RJ, Califf RM, Ide NC
The ClinicalTrials.gov Results Database — Update and Key Issues
NEJM 2011 Mar 3; 364:852-860
http://www.nejm.org/doi/full/10.1056/NEJMsa1012065#t=articleBackground

HSL19308
Silverman E
Astellas Loses Lawsuit Against French Med Journal
Pharmalot 2011 Mar 3
http://www.pharmalot.com/2011/03/astellas-loses-lawsuit-against-french-med-journal/

HSL19309
Silverman E
Amgen Execs Take The 5th Over Alleged Kickbacks
Pharmalot 2011 Mar 3
http://www.pharmalot.com/2011/03/former-amgen-execs-take-the-fifth-before-trial/

HSL19310
Forest Pharmaceuticals Sentenced to Pay $164 Million for Criminal Violations
Fierce Pharma 2011 Mar 3
http://www.fiercepharma.com/press_releases/forest-pharmaceuticals-sentenced-pay-164-million-criminal-violations

HSL19311
Taylor L
Thousands protest India/EU FTA's generic drug provisions
Pharma Times 2011 Mar 3
http://www.pharmatimes.com/Article/11-03-03/Thousands_protest_India_EU_FTA_s_generic_drug_provisions.aspx

HSL19465
Noah T
The Make-Believe Billion
Slate 2011 Mar 3
http://www.slate.com/articles/business/the_customer/2011/03/the_makebelieve_billion.html

HSL19312
Masoni M, Guelfi MR, Gensini GF
Online healthcare advertising needs regulation
BMJ 2011 Mar 3; 342:
http://www.bmj.com/content/342/bmj.c5778.extract

HSL19313
Hall D, Jones S, Iverson D
Disease awareness advertising – women’s intentions following exposure
Australian Family Physician 2011 Mar 3; 40:(3):143-147
http://www.racgp.org.au/afp/201103/41511

HSL19304
Silverman E
Boo! The NIH Grapples With Ghostwriting
Pharmalot 2011 Mar 2

HSL19305
Astellas' lawsuit against Prescrire: French court rules that Prescrire did not
Prescrire Int. 2011 Mar 2
http://english.prescrire.org/en/81/168/46799/0/NewsDetails.aspx

HSL19306
Le laboratoire Astellas Pharma perd son procès contre la revue Prescrire
Dépêche AFP 2011 Mar 2
http://www.france24.com/fr/20110302-le-laboratoire-astellas-pharma-perd-son-proces-contre-revue-prescrire?quicktabs_1=0

HSL19302
Arnold M
Much ado about mommy bloggers, mobile apps and paid posts
Medical Marketing & Media 2011 Mar 2
http://www.mmm-online.com/much-ado-about-mommy-bloggers-mobile-apps-and-paid-posts/article/197410/

HSL19299
Aston G
Navigating The Future Of DTC Advertising
MediaPost Marketing: Health Blogs 2011 Mar 2
http://www.mediapost.com/publications/?fa=Articles.showArticle&art_aid=145699

HSL19296
Iskowitz M
Off-label marketing offenses cost Elan $203 million
Medical Marketing & Media 2011 Mar 1
http://www.mmm-online.com/off-label-marketing-offenses-cost-elan-203-million/article/197340/

HSL19298
Roehr B
Medical journals with advertising are more likely than subscription journals to recommend drugs
BMJ 2011 Mar 1; 342:
http://www.bmj.com/content/342/bmj.d1335.extract

HSL19297
Pogachar M
Questions Linger on Social Media Regulations for Pharma
iHealthBeat 2011 Mar 1
http://www.ihealthbeat.org/features/2011/questions-linger-on-social-media-regulations-for-pharma.aspx#ixzz1FProUyyp

HSL19442
Sales Through Retail Pharmacies (Twelve months to January 2011)
ims 2011 Mar
http://view.respond.imshealth.com/?j=fe5a1579716304757611&m=fef31377726304&ls=fdfa17757666017475127374&l=fe9615727662037d73&s=fe21127975600c75701171&jb=ffcf14&ju=fe29167370610479771c79&r=0

HSL19288
Silverman E
Drugmakers Will Expand Which Sales Teams?
Pharmalot 2011 Feb 28
http://www.pharmalot.com/2011/02/drugmakers-will-expand-which-sales-teams/

HSL19292
Widely read free medical journals hype drugs: study
Reuters 2011 Feb 28
http://wtaq.com/news/articles/2011/feb/28/widely-read-free-medical-journals-hype-drugs-study/

HSL19291
Becker A, Dörter F, Eckhardt K, Viniol A, Baum E, Kochen MM, Lexchin J, Wegscheider K, Donner-Banzho N
The association between a journal's source of revenue and the drug recommendations made in the articles it publishes
CMAJ 2011 Feb 28;
http://www.cmaj.ca/cgi/content/abstract/cmaj.100951v1

HSL19322
Mackintosh M, Chaudhuri S, Mujinja PGM
Can NGOs regulate medicines markets? Social enterprise in wholesaling, and access to essential medicines
Globalization and Health 2011 Feb 28; 7:(1):4
http://www.globalizationandhealth.com/content/7/1/4

HSL19289
Silverman E
Abbott Pays Mommy Blogs To Review Similac App
Pharmalot 2011 Feb 28
http://www.pharmalot.com/2011/02/abbott-pays-mommy-blogs-to-review-similac-app/

HSL19290
Taylor L
EMA warned of potential 'conflicts of interest' involving former exec director
Pharma Times 2011 Feb 28
http://www.pharmatimes.com/Article/11-02-28/EMA_warned_of_potential_“conflicts_of_interest”_involving_former_exec_director.aspx

HSL19432
Kesselheim AS.
Covert pharmaceutical promotion in free medical journals.
CMAJ 2011 Feb 28; 183:(5):534-5
http://www.cmaj.ca/cgi/content/full/183/5/534

HSL19351
Krumholz HM
Examining an Ad for a Platelet-Inhibition Test
CardioExchange 2011 Feb 27
http://www.cardioexchange.org/examining-an-ad-for-a-platelet-inhibition-test/

HSL19284
Thacker T
All eyes on banned drugs
Indian Express 2011 Feb 26
http://www.indianexpress.com/news/all-eyes-on-banned-drugs/755175/0

HSL19294
Edwards J
J&J May Be Liable for Antipsychotic Kickback Scheme Despite “Legal” Contract
BNet 2011 Feb 25
http://www.bnet.com/blog/drug-business/j-j-may-be-liable-for-antipsychotic-kickback-scheme-despite-8220legal-8221-contract/7531

HSL19328
Braillon A
Stimulating the interest for conflicting scientific debates
The American Journal of Medicine Blog 2011 Feb 25
http://amjmed.blogspot.com/2011/02/stimulating-interest-for-conflicting.html

HSL19282
European drug regulator challenged over revolving door case involving former Director
ALTER-EU, HAI, ISDB 2011 Feb 25

HSL19295
Edwards J
Payola at Novartis: Theraflu App Got Rave Reviews From 'Sponsored' Bloggers
BNet 2011 Feb 25
http://www.bnet.com/blog/drug-business/payola-at-novartis-theraflu-app-got-rave-reviews-from-8220sponsored-8221-bloggers/7511

HSL19325
Mission Médiator et pharmacovigilance - Dr Alain Braillon
Assemblee Nationale 2011 Feb 240
http://www.assemblee-nationale.tv/chaines.html?dossier=Commissions&commission=MED_PHAR

Page 3 of 6 pages  < 1 2 3 4 5 >  Last ›

 

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...to influence multinational corporations effectively, the efforts of governments will have to be complemented by others, notably the many voluntary organisations that have shown they can effectively represent society’s public-health interests…
A small group known as Healthy Skepticism; formerly the Medical Lobby for Appropriate Marketing) has consistently and insistently drawn the attention of producers to promotional malpractice, calling for (and often securing) correction. These organisations [Healthy Skepticism, Médecins Sans Frontières and Health Action International] are small, but they are capable; they bear malice towards no one, and they are inscrutably honest. If industry is indeed persuaded to face up to its social responsibilities in the coming years it may well be because of these associations and others like them.
- Dukes MN. Accountability of the pharmaceutical industry. Lancet. 2002 Nov 23; 360(9346)1682-4.