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Healthy Skepticism Library item: 10587

Warning: This library includes all items relevant to health product marketing that we are aware of regardless of quality. Often we do not agree with all or part of the contents.

 

Publication type: Journal Article

Jureidini JN.
Not a trial of antidepressants
BMJ 2007 Jun 18; epub
http://www.bmj.com./cgi/eletters/bmj.39224.494340.55v1


Abstract:

This paper tells us something about the role of Cognitive Behaviour Therapy (CBT) in adolescent depression, but nothing about the use of drugs. The response rate is not strikingly different from what would be expected from placebo, and as with other studies of combinations of antidepressant and CBT, <1> we can draw no conclusions about the efficacy of antidepressants in the absence of a placebo arm…


Notes:

Rapid response to:
Goodyer I et al. Selective serotonin reuptake inhibitors (SSRIs) and routine specialist care with and without cognitive behaviour therapy in adolescents with major depression: randomised controlled trial. BMJ. 2007 Jun 7; [Epub ahead of print]

 

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Far too large a section of the treatment of disease is to-day controlled by the big manufacturing pharmacists, who have enslaved us in a plausible pseudo-science...
The blind faith which some men have in medicines illustrates too often the greatest of all human capacities - the capacity for self deception...
Some one will say, Is this all your science has to tell us? Is this the outcome of decades of good clinical work, of patient study of the disease, of anxious trial in such good faith of so many drugs? Give us back the childlike trust of the fathers in antimony and in the lancet rather than this cold nihilism. Not at all! Let us accept the truth, however unpleasant it may be, and with the death rate staring us in the face, let us not be deceived with vain fancies...
we need a stern, iconoclastic spirit which leads, not to nihilism, but to an active skepticism - not the passive skepticism, born of despair, but the active skepticism born of a knowledge that recognizes its limitations and knows full well that only in this attitude of mind can true progress be made.
- William Osler 1909