Healthy Skepticism Library item: 10587

Warning: This library includes all items relevant to health product marketing that we are aware of regardless of quality. Often we do not agree with all or part of the contents.

Publication type: Journal Article

Jureidini JN.
Not a trial of antidepressants
BMJ 2007 Jun 18; epub
http://www.bmj.com./cgi/eletters/bmj.39224.494340.55v1

Abstract:

This paper tells us something about the role of Cognitive Behaviour Therapy (CBT) in adolescent depression, but nothing about the use of drugs. The response rate is not strikingly different from what would be expected from placebo, and as with other studies of combinations of antidepressant and CBT, <1> we can draw no conclusions about the efficacy of antidepressants in the absence of a placebo arm…

Notes:

Rapid response to:
Goodyer I et al. Selective serotonin reuptake inhibitors (SSRIs) and routine specialist care with and without cognitive behaviour therapy in adolescents with major depression: randomised controlled trial. BMJ. 2007 Jun 7; [Epub ahead of print]